This effect was significantly blunted in 3-KO mice
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AOD9604 is a synthetic hexadecapeptide representing amino acids 176191 of the human growth hormone sequence, with a disulfide bridge between Cys182 and Cys189 that mirrors the structure of the native hGH C-terminal region
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Upregulated ANGPTL4 expression and suppressed LPL expression, along with their associated activities, are key fibrogenic factors in the mouse model of DKD (Srivastava et al., 2025a